When determining the moisture content of a sample, Coulometric Karl Fischer Titration offers accurate and reliable results. This technique is widely utilized in various industries, including Pharmaceuticals, Chemicals, and Food and Beverage, to analyze moisture levels in products.
Principle:
- The sample undergoing analysis must dissolve in a solvent. After that, an iodine-containing solution and sulfur dioxide are added to create the reaction environment.
- Electric current is added to the solution, leading to the generation of iodine through electrolysis. The iodine reacts with the water in the sample and consumes it.
- The titration endpoint is reached when all the water has been consumed, and the solution contains excess iodine. The amount of electric current required to reach this point is proportional to the water content in the sample.
Applications:
Coulometric Karl Fischer Titration is a versatile technique used in various industries for diverse applications:
- Pharmaceuticals: Moisture analysis of raw materials, finished products, and packaging materials.
- Chemicals: Determining moisture content in solvents, reagents, and petrochemicals.
- Food and Beverage: Moisture analysis of various food products, including dairy products, grains, and beverages.
Procedure:
The procedure is carefully followed to ensure accurate results:
1. Sample Preparation: The sample is weighed and dissolved in a suitable solvent compatible with the titration process.
2. Titration Setup: The titration cell is prepared with the necessary reagents and electrodes.
3. Titration: Electric current is passed through the solution until the titration endpoint is reached.
4. Calculation: The amount of electric current used during titration is calculated and used to determine the moisture content in the sample.
Advantages:
- Accurate and reliable moisture determination
- Wide range of sample applicability
- High sensitivity and low detection limits
- Well-established and standardized method
By utilizing Coulometric Karl Fischer Titration, industries can obtain precise and dependable moisture analysis results. Its accuracy, versatility, and compliance with industry standards make it an indispensable tool for ensuring product quality and regulatory compliance.